Procedural sedation and/or analgesia: a review

INTRODUCTION: In recent decades procedural sedation and/or analgesia (PS/PSA) have been widely used for diagnostic examinations and minimally invasive surgical interventions outside of the operating room. The recommendations presented in literature contain contradictory data related to indications, contraindications, baseline monitoring level, priority level protocols. OBJECTIVE: To perform an analysis current practice guidelines, randomized clinical trials (RCTs), review systematize on potential use sedatives narcotic analgesics sedation. MATERIALS AND METHODS: PubMed, Medline, Embase, eLibrary were searched PS/PSA RCTs, articles. RESULTS: describes levels increase difficulty risk complications. A comparative characteristic first- second-line drugs anesthesia is presented. Minimum requirements perioperative vital signs, pain are formulated. CONCLUSIONS: a planned or emergency procedure provides safe, comfortable successful performance mini-invasive interventions. principles interaction administration with basis regimens. scales has important practical value dynamics more fine management doses. There no absolute contraindications PS/PSA. popular area anesthesiologist resuscitator today. Russian Federation's lack regulatory documents makes it necessary develop guidelines.